12 Lichen Planus and Lichenoid Dermatoses

نویسندگان

  • Tetsuo Shiohara
  • Yoko Kano
  • LICHEN PLANUS
چکیده

• Idiopathic inflammatory disease of the skin, hair, nails and mucous membranes, seen most commonly in middle-aged adults • Flat-topped violaceous papules and plaques favor the wrists, forearms, genitalia, distal lower extremities and presacral area • Clinical variants include annular, bullous, hypertrophic, linear, ulcerative and lichen planopilaris • Histologically, there is a dense, band-like lymphocytic infiltrate with destruction of the epidermal basal cell layer • In this T cell-mediated autoimmune disorder, basal keratinocytes express altered self-antigens on their surface

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تاریخ انتشار 2006